The God-Machine, its angels, and the elements you mention are slated to play an important role in the nWoD setting, starting with the God Machine Chronicles, a fiction anthology soon to be followed up by an adventure sourcebook that will include revisions to the Storytelling System that could be considered a stealth "second edition." (These rules changes will be released as a free download.) This entity will also play a key role in the upcoming Demon game.
Other authors have spun off ideas from that section. To wit:
Danse Macabre, a sourcebook for Vampire: The Requiem, details a mini-Covenant called the Holy Engineers, who receive transmissions from the God Machine that they strive to interpret. The intended effect is "oracles in reverse" — they'll receive answers and missions to undertake with the goal of figuring out the question or inciting incidents.
Imperial Mysteries, the archmastery book for Mage: The Awakening, says this:
It might also be possible to secretly change the world into an occult engine for a Fallen god: a Mystery Play that returns it to power. The ententes believe at least one such "God Machine" already exists.
The following contains spoilers for "These Mortal Engines" in the Promethean: the Created sourcebook, Saturnine Night.
The God Machine, or an aspect of it, makes an appearance at the climax of this adventure, "offering" the player characters a chance to become human. The choice to activate or destroy the machine is crucial to the final act.