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There are a number of D&D 4e character creation options that allow players to substitute one ability score in place of another under certain conditions. Here are some examples:

Auspicious Birth or Born Under A Bad Sign backgrounds

Benefit: You substitute your highest ability score for Constitution to determine your initial hit points.

... or ...

Melee Training feat

Benefit: Choose an ability other than Strength. When you make a melee basic attack using a weapon with which you have proficiency, you can use the chosen ability instead of Strength for the attack roll. In addition, you can use half of that ability’s modifier, instead of your Strength modifier, for the damage roll.

What options are there for 4e characters to substitute one ability score for another?

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closed as not a real question by Brian Ballsun-Stanton May 8 '13 at 1:32

It's difficult to tell what is being asked here. This question is ambiguous, vague, incomplete, overly broad, or rhetorical and cannot be reasonably answered in its current form. For help clarifying this question so that it can be reopened, visit the help center.If this question can be reworded to fit the rules in the help center, please edit the question.

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This question is too broad. Please tell us which thing you're trying to accomplish. –  Brian Ballsun-Stanton May 8 '13 at 1:32
    
@Corion are you looking for something like basing your Init. off a stat other than dex or changing how MBAs work? –  Joshua Aslan Smith May 8 '13 at 12:27
    
Trying to figure out legitimate alternative stat combinations to use with classes (such as what can substitute for AC or whether I could use CHA to make RBA's). These questions come up so many times when building characters, and I could not find a comprehensive list anywhere online. I didn't realize it wasn't a good fit for SE when I posted it. I'm compiling a list on the Giant In The Playground forums if anyone wants to know or help out. –  Corion May 9 '13 at 23:00
    
Here is the thread where the list is being compiled, for those interested: Ability Score Substitution –  Corion May 11 '13 at 5:32