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I am aware of the fact, that a ghoul does not get his master's clan flaw in full, as they are not Embraced and do not possess the Beast. However, some fluff suggests that in many cases subtle changes occur in ghouled mortals and animals. Nosferatu animals are prone to mutation and are usually bigger and badder. Toreador ghouls find themselves fond of works of art.

Revenant Ghoul Families carry their own flaws, as the Bratovitch get the Brujah equivalent etc.

So how is it with the thrall ghouls? Do they get some features of their masters clan, mechanically speaking, or not? I would be specifically interested if Nosferatu ghouls suffer loss of the Appearance ability, does their appearance change considerably?

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I need to point that ghouls do have a Beast, only weaker than that of a vampire (frenzy and rottscrheck difficulties are 2 points bellow of that marked in the table). –  Mu_ Jul 12 at 19:00

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up vote 7 down vote accepted

Ghouls that are feeded for a long time, as well as those that are frequently overdosed suffer a lesser version of the clan weakness. Here comes what Ghouls: Fatal Addiction tells:

A few clans' vitae possesses contagious properties. Ghouls imbibing/injecting five or more Blood Points from certain clans must make a Stamina roll (difficulty 5) or "inherit" a lesser form of the domitor's weakness; this last until the vita has been purged (i.e., the ghoul holds fewer than five Blood Points from one clan).

I think this contradicts a little other books where ghouls inherited weaknesses last more than that overdose. But I cannot recall which books. Note that it also tells that only some clans' vitae is contagious. Let's see the given examples:

The clans for which this rule most commonly applies are: Brujah (a ghoul "pumped" on Brujah blood frenzies at difficulties equal to those of a non-Brujah vampire[*]); Malkavaian (ghoul gains a mild Derangement); Nosferatu (Appearance drops by one or two points, but no lower than 1); Ventrue (ghouls gains a marked preference for Ventrue blood --possibly endangering the domitor); Setite(ghoul develops painful [-1 to Dice Pools] rashes when in direct sunlight; furthermore, many Setites have the Addictive Blood Merit); and any Sabbat (no mandatory effect, but remember the possibility of contracting disease via Vaulderie). At the Storyteller's discretion, vitae from other clans may cause similar effects.

[*] Note that overdosed ghouls already have increased frenzy rating, so you should adjust a little here.

Why those clans? I guess because they were the ones that they could thought better mild versions of the clan's weaknesses. Anyway, one can easily imagine a mild version of any weakness, and they left room to you for coming up with your own.

Note that there is a V20 Ghouls supplement coming, and I think we will see changes to these mechanics, and even a complete list of clans and weaknesses.

As a side note, I remember a funny conversation when people tried to imagine these weaknesses applying to animal ghouls (a Ventrue dog only wanting to eat some brand of food, a Tremere antitribu bird identified as Tremere antitribu by magic users, a Gangrel cat that gains other animals features, an Assamite panther that can no longer drink Kindred blood [or addicted to it],...).

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One of the book which contradicts this is Dark Ages: Vampire. In this, it is said that a ghoul with 5 or more blood points gains the Domitor clan weakness (the full weakness) as long as she still has 5 or more blood points. It is one of those points in which I would recommend the Storyteller tuning with her imagination to achieve the effect she desires. –  Mu_ Jul 12 at 18:58

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