The answer for the question "Can Mage Hand grab opponents' items?" says that "since it's assumed in 5e that picking up an object can be part of a creature's movement during its turn and can pick up before an attack, disarming becomes pretty pointless." But is it really pointless?
The optional rule for disarming says
A creature can use a weapon attack to knock a weapon or another item from a target's grasp. The attacker makes an attack roll contested by the target's Strength (Athletics) check or Dexterity (Acrobatics) check. If the attacker wins the contest, the attack causes no damage or other ill effect, but the defender drops the item. The attacker has disadvantage on its attack roll if the target is holding the item with two or more hands. The target has advantage on its ability check if it is larger than the attacking creature, or disadvantage if it is smaller. (Dungeon Master's Guide 271)
Are there any bonus actions that a PC could take to prevent the item from being recovered? A cantrip or spell that can be used as a bonus action to prevent the weapon's recovery? Could mage hand move the item far away? Can the PC simply pick up the item adding it to inventory before the opponent's turn? (Does putting it in inventory, rather than wielding it, force the opponent to do a pick pocket to get it back rather than a disarm attack back?) Would throwing it into a river or kicking it over a cliff be doable by the PC or would another PC be required to expend an action?
What can a PC or the PC's allies do to prevent a disarmed item from being recovered?