I was looking through this article, reading about a portable hole + bag of holding combination as a projectile weapon and I was thinking about the end effect.
Placing a bag of holding inside an extradimensional space [...] instantly destroys both items and opens a gate to the Astral Plane. The gate originates where the one item was placed inside the other. Any creature within 10 feet of the gate is sucked through it to a random location on the Astral Plane. The gate then closes. The gate is one-way only and can't be reopened.
Things and creatures are obviously sucked into the Astral Plane, but are they necessarily killed or destroyed? If this was used as a weapon to throw a human sized enemy into the Astral plane would they survive?
Normal spells can safely send people and things to the Astral Plane but what if they're forcibly sent there by a bag of holding + portable hole combination? The Gith can survive there so I assume it is at least somewhat hospitable to humanoid life.