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Casting blindness-deafness on a creature with blindsight:
A monster with blindsight can perceive its surroundings without relying on sight, within a specific radius.
Attack rolls against the creature have advantage, and the creature's attack rolls have disadvantage.
Do attack rolls have advantage against a creature with blindsight that has been blinded?
Technically yes, since nothing about Blindsight says that it prevents the creature from being blinded. (And in some situations it might make sense, when a creature's blindsight is a secondary sense instead of their primary one).
In practice, all the examples of creatures I can find that have the Blindsight special ability are also explicitly immune to the Blindness condition (in the "Condition Immunities" block), so for those being Blinded will not bother them one bit.
