I'm about to start running Waterdeep: Dragon Heist, and one of the characters is a Knight of the Silver Chalice. I believe that this organization was originally founded in Waterdeep. Do they still have a presence there (circa 1492 DR)?
As far as I can tell, the Order of the Silver Chalice is either no longer present in Waterdeep or they have gone into hiding.
Possible spoilers for Waterdeep: Dragon Heist (p. 117):
Jeremy Crawford stated in a 2015 tweet that "Siamorphe and the Knights of the Silver Chalice endure", but did not provide any additional details.