NPCs are going to poison the party while they sleep, do the players have disadvantage on their saves?
I just started a campaign with a group where I was once a player. Their lvl 5 characters are on a ship sleeping in the spare crew cabin, but they do not know that it's a pirate ship. When they went to sleep it was approximately 3pm and the Pirate Captain found out that they may want to leave before her plan to get some treasure is put through. So she wants more info on the characters and I was planning to have the characters while they are sleeping be exposed to 'Essence of Ether' which is dropped down a small hole above deck. Since they are asleep and STR and DEX checks auto fail and you can't really stop yourself from breathing mid sleep, do they have disadvantage on a CON save?