Years ago I was a player in a game that started as a really intense, high action D&D one shot and then within about an hour we learnt that we were in a simulation designed to help us function better as a trouble shooter team. We were playing 3rd or 4th edition D&D but I know our GM at the time used materials from a wide range of sources when creating his campaigns and one-shot adventures.
The effect was made even better by the fact none of us knew we were getting into a Paranoia one-shot. At the time the GM said he had taken the idea from a published campaign but I can’t find what that might have been.
I know that there is an old adventure Alice through the mirror shades that melds together Paranoia and Cyberpunk.
Is there anything similar for D&D or any other role play system?
I will say that our group loves it when I throw together a Paranoia adventure for them. My printer not so much, so many forms to print off.