The warlock I DM for is considering Blade of Disaster (from Tasha's Cauldron of Everything) for his 9th level Arcanum, and I have just now read its description. The blade may be directed at:
a creature, loose object, or structure within 5 feet of the blade.
This is the first time I recall reading the phrase "loose object", and a quick word search of the PHB netted me only seven uses of "loose", with only two fitting the context: "loose coins" in the table of Sailor Flaws, and "loose, lightweight materials" in the description of wind wall. The standard English usage of 'loose' might be 'free, not attached'. However, that does not appear to be the use intended for the blade of disaster. Given a prisoner manacled to a wall, I would find it strange to rule that the blade could attack the prisoner or the wall, but not the manacle, since the manacle is not a loose object in the sense that it is attached to both the wall and the prisoner.
Rather, I think what the description of the blade is trying to convey is what the PHB called 'objects that are not worn or carried', and cf. the descriptions of the spells burning hands, firebolt, and true polymorph. In this sense, since the manacle is neither worn nor carried it is a legitimate target for the blade.
Are there other non-PHB uses of the phrase 'loose object', and can we tell from them what is meant by the words?