This question already has an answer here:
What I'd really like to do, and don't think I have right tools/approach, is to emotionally manipulate my players into making sub-optimal - even bad - decisions using the NPCs I present them with.
"I can't believe John did that to Jill, let's get him!"
"Little Billy is going to die unless we do X"
"I know she said she'd destroyed that town but c'mon, it's Claire, she's our friend..."
Making NPCs stand out and memorable isn't the point here, I want the players to really care about them.
Can this be done?