Let's imagine you get to go to International Space Station and you like to roll dice. But they don't stop flying around the station because you're in space where gravity is not high enough. How can this problem be solved?
You use computers instead of dice.
Computers have pretty good pseudo-random number generators these days (assuming you're not using them for cryptographic purposes). I count at least a dozen free dice apps on the Android app store; I'd imagine there are at least a dozen on the Apple app store as well. It's also not very hard to write your own (less than 100 lines of code). Or if you want true randomness and have Internet access, there are services like random.org that sample atmospheric noise or use similar processes to provide actual random numbers.
If you're on the space station and there are no computers available, you probably have higher priorities than playing RPGs.
One way I can see to roll actual dice (carefully) would be to use a magnetic plate (alternating north and south pole domains, like flexible magnet tape) and steel dice. As long as you roll gently enough the dice don't bounce too high, you'll get an honest roll and the dice will stick to the plate.
Another method would be to use a ball bubbler mechanism, similar to the ones used in lottery drawings or bingo parlors -- these would work equally well in microgravity, though the dice and magnetic plate would fit better in an astronaut's personal items weight allowance.
A possible third way would be a vacuum surface -- like an air hockey table running backward -- with conventional dice. Less adhesion than magnetic table and steel dice, but more rolling action.