I am a new DM. For my first campaign, I am going to kill off the entire race of non-Drow elves, except for the PCs who are the only survivors. Later on, I will be having them discover other survivors, good and bad, but not many. The world I am using is the Forgotten Realms. It happens all on the same day but over the course of 1 day, in the year 1374, right after The Silence of Lolth.
For clarity, the elves were killed off by a blood curse and all gear owned by elves has become tainted and no longer carries any of the magic abilities it once had. PC's could loot for better gear but it would be no better than what they already might have.
I am using C&C as my ruleset but using Faerun from D&D3.5 as my world.
Is there anything in the game or setting that the elves are specifically tied to, that by eliminating them would cause my campaign to be unplayable?