Edit: Would it be absurd to consider 6d10 of force damage, originating in the gut of a PC, as described below from the PHB to be immediately fatal? As-written it does a fair amount of damage (avg. 33) in a (ten foot radius?) area around the point of mixture.
I'm reading through the DMG in preparation for a meeting tomorrow with my group and, seeing as they are all newly minted level 4 "heroes", I've decided it is time for some magic items to enter the fray. The BBEG they are likely going to enter service with is going to allow them access to a portion of his armory and there will undoubtedly be scrolls and potions involved.
Reading the Variant: Mixing Potions got me worried, as a 01 roll of a d100 results in:
01: The mixture creates a magical explosion, dealing 6d10 force damage to the mixer and 1d10 force damage to each creature within 5 feet of the mixer.
This is all well and good, but there is this line above the table:
A character might drink one potion while still under the effects of another,
So if a PC decides to drink two potions, and you roll a 01 on the miscibility roll, wouldn't that effectively kill the PC? I don't care if you have the intestinal fortitude of an igneous rock, really, a forceful explosion (unless the damage roll is extremely low?) will wreck your internal organs wouldn't it?
Obviously the chances of this sort of thing happening are minute at best, but I can't imagine something exploding inside your chest cavity as anything but catastrophic, even with a low roll...