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The spell Remove Disease states:

Certain special diseases may not be countered by this spell or may be countered only by a caster of a certain level or higher.

I have not yet found any diseases that state that they cannot be cured by said spell. Therefore I am asking for a clarification.

Is the difference between extraordinary and supernatural diseases connected to Remove Disease's limitation?

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Supernatural diseases are more likely to be resistant to Remove Disease, but not all are.

Mummy Rot (scroll down a bit, there isn't an anchor) is a SU disease, which requires a Caster Level of 12 to remove. Lycanthropy is a SU disease chich can be cured by Remove Disease at any level, but with a time restriction (within 3 days of contracting the disease). On the other hand, the epic Hunefer has a SU disease which can be cured by Remove Disease without respect to CL.

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    \$\begingroup\$ For completion's sake: The spell Scourge (Spell Compendium) inflicts a magical (not SU) disease that may only be healed by remove disease after casting a remove curse or break enchantment. \$\endgroup\$
    – SPavel
    Mar 19, 2016 at 1:04

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