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Shadowrun has a disease called Human-Metahuman Vampiric Virus. Depending on the strain of the disease, it turns humans (and some non-human) animals into different types of creatures of legend. HMHVV-I turns humans into vampires but turns elves into banshees. HMHVV-II tends to result in more feral creatures, while HMHVV-III (Kreiger-strain) turns any kind of metahuman into a ghoul.

Do any published Shadowrun adventures for any edition feature non-Ghoul Infected as an antagonist, objective, or Mr. Johnson? If so, which ones?

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Sprawl Wilds for the 5th edition has an adventure called Manhunt.

The runners don't know about it until they do some legwork, but a wendigo (HMMVV-I ork) makes trouble on a farm near Seattle.

Mission summary:

Fifteen years ago Seattle was plagued by a number of vicious animal attacks. Now these attacks seem to be on the rise again.

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I know that the Runner's Companion adventure (On the Run) has not only a vampire, but a gang of them. A major character in the entertainment business is actually a vampire.

Elvis is a vampire.

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