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The Fabricate Disguise spell basically creates a non-magical disguise in an instant (1 standard action) and allows the caster to make a Disguise skill check to determine how effective it was. It uses materials the caster already has available.
The Disguise skill takes (1d3 × 10) minutes of time to create.
Is there any difference between the two besides the time required?
No, Fabricate Disguise simply allows you to use a 1st level spell slot to forgo the 10-30 minutes it would normally take to change your appearance.
This seems like a reasonable use of a spell slot, being that it doesn't give you any particular bonus to the check. It would be very situational if it became useful- you'd have to have less than the normal amount of time to make a disguise (which most people would have prepared ahead of time).
