If a blind character acquired some way (whether though homebrew classes, blessings or magic items) of gaining blindsight or tremorsense, that character would be able to use those senses without issue. However, would the same be true if said character gained truesight? Is truesight a different sense to your regular vision, or is it a modification to it (and thus a blind character's vision would be modified to allow truesight, but he would still have a vision range of 0ft, rendering the modification useless)?
Truesight is described as something that allows someone to "see" things better than common sight. You need sight to see, so probably truesight won't work
A monster with truesight can, out to a specific range, see in normal and magical darkness, see invisible creatures and objects, automatically detect visual illusions... [MM Pg 9, emphasys mine]