What happens if the beads from a [*necklace of fireballs*][1] are used as ammunition for a firearm? Would *loading* count as *throwing* so that when the bead stops in the firearm's barrel, the bead explodes? If not, should the bead make a Reflex saving throw (DC I don't know) to avoid detonation? If a bead were fired, should the bead detonate on impact without dealing normal firearm damage, or should the bead deal normal damage, stop in the struck target's body, and detonate there, eliminating the target's Reflex saving throw? 


  [1]: http://www.d20pfsrd.com/magic-items/wondrous-items/wondrous-items/m-p/necklace-of-fireballs