The TARGET meaning is definitely not the only one used in the rules, as spells like Fireball have one TARGET you choose (a point in space), but may also effect a number of creatures (and flammable objects) in the area of effect. Affected creatures are are explicitly described as targets in the spell's rules (emphasis added):
Another area where this comes upthat is somewhat ambiguous is the destination of teleportation spells. As the formal rules for picking spell TARGETs say, you normally need "a clear path to athe TARGET":
One surprising consequence of this (as the podcast discusses) is that you can't cast spells through glass windows, since they count as total cover (personally I'd interpret cover relative to the type of effect, so a window would not provide cover to a non-physical effect like Hold Person, but it would indeed cause a Fireball to explode prematurely, though the blast wouldmight destroy the window and spreadlet the AOE spread outside). But most teleportation spells are phrased such that you don't explicitly TARGET your destination, even though your arrival will clearly affect the place. So it's unclear if you need to a clear path to the destination or not. For some spells like Dimension Door and Teleport, it's pretty obvious that you're not expected to have a clear path, since they have specific rules for how you pick your destination even if you can only describe it or have had it described to you (an example given in the rules: "upward to the northwest at a 45- degree angle, 300 feet"). But other spells like Misty Step specifically say you need to see your destination, which makes it ambiguous if you can use themthe spell to teleport through transparent total cover (e.g. a window). The explicit TARGET of Misty Step is the caster (it has range self), but some spells are less carefully written, and so we find spells like Thunder Step (from XGtE) which specifies the distance you can teleport with its range, making a stronger case for the destination being a TARGET too.