What would happen if beads from a necklace of fireballs were loaded into a firearm as ammunition? Would loading count as "throwing" the bead, so as soon as the bead stopped in the barrel, it would explode? If not, then should the bead have to roll a reflex save to avoid detonation, and what should be the DC? If it were to be propelled, should it detonate on impact without dealing normal firearm damage, or should it deal normal damage, stop in the body and detonate there, without giving a victim chance for a reflex save?