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deleted 45 characters in body
Someone_Evil
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I'll cover things again, so as to try to get a single, complete list, and because I think there are some additional points to mention. I make the split into two categories:

Buffing your own save DC:

  • Improving your wisdom score up to 20:

  • Ability score improvements

  • Feats: Resilient, Observant, Elven Accuracy (XGtE; Elves, half-elves)

  • Ioun stone of Insight

  • Improving your Wisdom score beyond 20:

  • Book of Exhalted Deeds (upto 24)

  • Tome of Understanding (up to the innate max of 30)

  • Deck of Many Things: Star (upto 24) (pull cards from the deck at your own risk)

  • Increasing your proficiency bonus

  • Ioun stone of Mastery (+1)

Weakening the target's constitution save:

  • Negative modifier

  • Bane (1d4)

  • Wild Magic Sorcerer's Bend Luck (1d4)

  • Disadvantage:

  • Bestow Curse

  • Sickening Radiance (through granting exhaustion)

  • Staff of Withering

  • Claw of the Wyrm Rune's Wyrm Ward (Storm Kings Thunder; Consumes the item, requires 8h prep work on the area, and only works on dragons)

  • Replacing the roll through Wizard School of Divination's Portent

Someone_Evil
  • 48.9k
  • 8
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  • 260