With respect to your specific "Is making all powers reliable" too powerful, I think there are two parts to the question - "Are you creating an imbalance between your players, where one benefits greatly, while others lose out?" and "How as a DM do I adjust threats to accommodate the stronger characters?"
For the imbalance between players component, you are probably giving classes like the Barbarian (with their "hit one, guy once, but bad" attacks) a bigger boost than classes like the Sorcerer or Wizard (with their attack many so miss all less often) and classes like the Fighter who have toned down dailies that actually are reliable.
To solve the fighter problem, I would give them either a bonus +Strength or a +W damage on powers that are currently reliable.
For powers that have multiple targets, I would allow a player to designate one target as the primary, and if the primary is missed, and the player wants to retain the power, then all targets (or maybe just all enemies) are also missed.
For Rangers doing the daily versions of Twin Strike, I probably wouldn't make much adjustment, as they are on the high side of damage output, so benefiting less from such a house rule isn't as big an issue.
Additionally classes that have effects on their daily attack powers "fly 10 squares and attack" will get the effect parts more often than they should. (Again, the Barbarian thanks you while the Warden looks on enviously, as the Barbarian could conceivably uses a Rage power with a non-proficient weapon so he can miss and get to use the Rage again in another encounter) - though this scenario can be dealt with by applying your suggested miss rules to effects as well.
Finally, if you have psionic classes you need to figure out how power points fit in...
As to the second part about adjusting threats, I would suggest that making this same change to monsters for recharge and encounter powers would probably do the trick, or at least come close. However, I find bookeeping of monsters annoying, so I'd be tempted, for most recharge and encounter powers to just make them at-will unless that really, really felt wrong for the monster.